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مقاله
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Abstract
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Title:
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traumatic Endophthalmitis prophylaxis with Oral ciprofloxacin in comparison to Intravenous cephazolin / gentamicin
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Author(s):
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dehghani alireza, akhlaghi mohammadreza, pourazizi mohsen
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Presentation Type:
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Oral
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Subject:
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Posterior Segment
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Others:
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Presenting Author:
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Name:
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Alireza Dehghani
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Affiliation :(optional)
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eye research center, isfahan university of medical sciences,isfahan,iran
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E mail:
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adehghani45@yahoo.com
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Phone:
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2363685
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Mobile:
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09133109705
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Purpose:
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The aim of this study was to evaluate the efficacy and clinical outcome of oral ciprofloxacin vs. Intravenous cephazolin / gentamicin for prevention of endophthalmitis after penetrating ocular trauma
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Methods:
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This was a retrospective, single-center study, including all cases of penetrating ocular trauma seen in the Feiz hospital, a tertiary referral eye hospital in Isfahan,
Iran, between 2011 and 2017. Data systemically recorded for each patient included clinical, ophthalmological, and demographic findings by a trained medical record abstractor or ophthalmologist reviewing patient records
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Results:
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645 patients in cephazolin / gentamicin and 273 patients in oral ciprofloxacin groups were included in the study. Our study showed that the incidence of endophthalmitis was not significantly different between two groups. (p-value: 0.463) in patients with either sharp or blunt penetrating ocular trauma
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Conclusion:
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Oral ciprofloxacin as a prophylactic treatment could prevent post-traumatic Endophthalmitis as effective as injectable cephazolin / gentamicin. Due to easier consumption of oral ciprofloxacin and lower systemic complications, in all patients with penetrating eye trauma,
oral administration of ciprofloxacin is preferable to intravenous or intra-muscular types of antibiotics to reduce the risk of post-traumatic Endophthalmitis
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Attachment:
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