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مقاله
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Abstract
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Title:
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Patients’, Globe, and Vision Survivals in Rhino-Orbito-Cerebral Mucormycosis
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Author(s):
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Mohsen Bahmani Kashkouli, Parya Abdolalizadeh, Mitra Oghazian, Yasaman Hadi, Nasser Karimi, Mahya Ghazizadeh.
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Presentation Type:
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Oral
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Subject:
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Ophthalmic Plastic and Reconstructive Surgery
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Others:
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Presenting Author:
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Name:
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Mohsen Bahmani Kashkouli
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Affiliation :(optional)
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Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences
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E mail:
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mkashkouli2@gmail.com
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Phone:
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Mobile:
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09121777003
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Purpose:
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To report the frequency and factors affecting patients’, globe, and vision survivals in rhino-orbito-cerebral mucormycosis (ROCM).
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Methods:
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This is a retrospective study of 63 patients (79 eyes) with biopsy proven ROCM at a university hospital (2008-2016). Systemic and ophthalmic manifestations, imaging, management, and final outcomes were recorded. Globe survival was defined as no exenteration and vision survival as final visual acuity of light perception and more.
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Results:
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Mean age was 55.5 (SD:12.9) years old with no gender preference. Diabetes was the most common underlying disease (68.3%). Patients’ survival was observed in 57.1% (36/63). Presence of frozen eye (OR=4.6), nasal mucosal involvement (OR=7.3), and shorter duration of anti-fungal therapy (OR= 1.03) were significantly associated with lower patients’ survival. Exenteration did not significantly change the survival. Globe survival was detected in 43% (34/79). Higher white-blood-cell (WBC) count was associated with a lower globe survival (P=0.02). Vision survival was observed in 25.3% (20/79) in whom younger age was significantly associated with a worse vision survival.
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Conclusion:
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Patients’, globe, and vision survivals were 57%, 43% and 25%. Exenteration did not affect the patients’ survival. While frozen eye, nasal mucosal involvement, and shorter duration of treatment were significantly associated with a lower survival, higher WBC count significantly increased the risk of exenteration.
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Attachment:
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